Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis
Wang, J., Li, Y., Wang, P. et al. Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis. Cell Stem Cell. (2020). https://doi.org/10.1016/j.stem.2020.04.001
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piRNA-30473 contributes to tumorigenesis and poor prognosis by regulating m6A RNA methylation in DLBCL
Han, H., Fan, G., Song, S. et al. piRNA-30473 contributes to tumorigenesis and poor prognosis by regulating m6A RNA methylation in DLBCL. Blood. (2021). https://doi.org/10.1182/blood.2019003764
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Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment
Zhou, C., Zhang, Y., Yan, R. et al. Exosome-derived miR-142-5p remodels lymphatic vessels and induces IDO to promote immune privilege in the tumour microenvironment. Cell Death Differ. (2021). https://doi.org/10.1038/s41418-020-00618-6
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Glycyrrhizic Acid Improves Cognitive Levels of Aging Mice by Regulating T/B Cell Proliferation
Jiang, R., Gao, J., Shen, J. et al. Glycyrrhizic Acid Improves Cognitive Levels of Aging Mice by Regulating T/B Cell Proliferation. Front Aging Neurosci. (2020). https://doi.org/10.3389/fnagi.2020.570116
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An unexpected role for p53 in regulating cancer cell–intrinsic PD-1 by acetylation
Cao, Z., Kon, N., Liu, Y. et al. An unexpected role for p53 in regulating cancer cell–intrinsic PD-1 by acetylation. Sci Adv. (2021). DOI: 10.1126/sciadv.abf4148
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Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer
Wang, S., Qu, Y., Xia, P. et al. Transdifferentiation of tumor infiltrating innate lymphoid cells during progression of colorectal cancer. Cell Res. (2020). https://doi.org/10.1038/s41422-020-0312-y
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Three epitope-distinct human antibodies from RenMab mice neutralize SARS-CoV-2 and cooperatively minimize the escape of mutants
Nie, J., Xie, J., Liu, S. Three epitope-distinct human antibodies from RenMab mice neutralize SARS-CoV-2 and cooperatively minimize the escape of mutants. Cell Discov. (2021). https://doi.org/10.1038/s41421-021-00292-z
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Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1
Park, J.-J., Thi, E.P., Carpio, V.H. Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1. Nat Commun. (2021). https://doi.org/10.1038/s41467-021-21410-1
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Targeting macrophage checkpoint inhibitor SIRPα for anticancer therapy
Liu, J., Xavy, S., Mihardja, S. et al. Targeting macrophage checkpoint inhibitor SIRPα for anticancer therapy. JCI Insight. (2020). https://doi.org/10.1172/jci.insight.134728
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Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist
Upadhyaya, P., Lahdenranta, J., Hurov, K. et al. Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist. J Immunother Cancer. (2021). http://dx.doi.org/10.1136/jitc-2020-001762
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