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    SITC 2023: Development of a Preclinical CD98HC Mouse Model for Therapeutic Studies

    October 17, 2023
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    • mRNA expression analysis: Mouse Cd98 mRNA was detected in kidney tissue from wild-type mice, while human CD98 mRNA was detected in B-hCD98HC mice. • Protein expression analysis: Human CD98 was exclusively expressed in B-hCD98HC mice and was associated with the brain microvascular endothelium of B-hCD98HC mice.