This B-luc-GFP Raji cell line expresses firefly luciferase as a marker of Raji cells. Luminescence can be observed B-luc-GFP Raji cells.
Efficacy of Anti-Human CD47 Antibodies in Immunodeficient B-NDG mice
B-luc-GFP Raji cells were injected intraperitoneally into B-NDG mice and observed with a small animal imager. Animals were enrolled into either the control group or the treatment group (n=6) when the tumor fluorescence intensity reached 1.5E6. (A) Various anti-human CD47 antibodies inhibited tumor growth, as indicated by tumor fluorescence intensity ± SEM, (B) without negatively impacting mean body weight (± SEM) changes.