Basic Information
Common Name
B-luc-GFP Raji
Catalog Number
310670
Aliases
NA
Disease
Burkitt’s lymphoma
Organism
Human
Strain
NA
Tissue types
Lymphoma
Tissue
Lymphoblast
Application
B-luc-GFP Raji cell line can be used to evaluate anti-cancer drugs in burkitt’s lymphoma in vivo.
Description
This B-luc-GFP Raji cell line expresses firefly luciferase as a marker of Raji cells. Luminescence can be observed B-luc-GFP Raji cells.
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Efficacy of Anti-Human CD47 Antibodies in Immunodeficient B-NDG mice
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B-luc-GFP Raji cells were injected intraperitoneally into B-NDG mice and observed with a small animal imager. Animals were enrolled into either the control group or the treatment group (n=6) when the tumor fluorescence intensity reached 1.5E6. (A) Various anti-human CD47 antibodies inhibited tumor growth, as indicated by tumor fluorescence intensity ± SEM, (B) without negatively impacting mean body weight (± SEM) changes.
