Basic Information
Cell Line Name
Raji Tg(luciferase)/Bcgen
Common Name
B-luc-GFP Raji
Catalog Number
310670
Cell Type/Disease
Burkitt’s lymphoma
Culture Properties
Suspension
Resistance
Blasticidin S HCl (BSH)，10 μg/mL
Medium
RPMI-1640+10%FBS+2μg/mL BSH+1% L-Glutamine+1% NEAA+1% Sodium pyruvate+1%HEPES
Digestive solution
N/A
Cryopreservation
Medium
95% (Med)+5% DMSO
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Targeting Strategy
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Efficacy of Anti-Human CD47 Antibodies in Immunodeficient B-NDG mice
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B-luc-GFP Raji cells were injected intraperitoneally into B-NDG mice and observed with a small animal imager. Animals were enrolled into either the control group or the treatment group (n=6) when the tumor fluorescence intensity reached 1.5E6. (A) Various anti-human CD47 antibodies inhibited tumor growth, as indicated by tumor fluorescence intensity ± SEM, (B) without negatively impacting mean body weight (± SEM) changes.
