B-Apoe KO mice
May 20, 2019
B-p53 KO rats
May 20, 2019
Tp53tm1/Bcgen rats are a useful model for studying tumor formation, screening in vivo carcinogenicity, and examining the efficacy of therapeutic agents. The Tp53 KO rat model was developed using targeted TALEN technology in the Sprague-Dawley strain. This model possesses a 12 bp deletion and 2 bp insertion within Exon 2 of Tp53 on chromosome 10. […]
B-SDG rats
May 20, 2019
The recombinant-activating gene 2 (Rag2) plays an important role in the rearrangement and recombination of the genes of immunoglobulin and T cell receptor molecules during the initiation of V(D)J recombination. Loss of Rag2 protein leads to no mature T and B cells, the critical components of the adaptive immune system. Il2rg is known as the […]
