B-hPD-L1/hTIM3 mice
May 22, 2019
B-hSIRPA/hCD47 mice
May 21, 2019
B-hPD-1/hSIRPA/hCD47 mice
May 21, 2019
B-Pdgfrb-iCre Mice
May 21, 2019
B-hPD-L1/hSIRPA/hCD47 mice
May 21, 2019
B-Prrx1-iCre Mice
May 21, 2019
B-Apoa4 KO rats
May 21, 2019
The Apoa4 KO rat was developed using targeted TALEN technology in the Sprague-Dawley strain. This model possesses an 8 bp deletion within Exon 2 on chromosome 8 causing a protein frame shift. This strain was maintained by mating homozygous males with homozygous females on a Sprague-Dawley genetic background.
B-Sp7-iCre mice
May 21, 2019
The Sp7 gene is a C2H2-type zinc finger transcription factor of the SP gene family and putative master regulator of bone cell differentiation. In this strain, Cre recombinase expression is under the control of Sp7 promoter. When crossed with a strain containing a loxP site-flanked sequence of interest, Cre-mediated recombination results in deletion of the […]
B-hHER2 MC38
May 21, 2019
B-hPD-L1 MC38 Plus
May 21, 2019
The mouse Pd-l1 gene was replaced by the coding sequences of human PD-L1 and luciferase in B-hPD-L1 MC38 plus cells. Human PD-L1 is highly expressed on the surface of B-hPD-L1 MC38 plus cells. B-hPD-L1 MC38 plus cells have the capability to establish tumors in vivo and can be used for efficacy studies.
