Humanized CD36 mouse model supports the preclinical evaluation of therapeutic candidates targeting CD36 Used in this study: B-hCD36 mice Read more
ZNF582 overexpression restrains the progression of clear cell renal cell carcinoma by enhancing the binding of TJP2 and ERK2 and inhibiting ERK2 phosphorylation Used in this study: B-NDG Mice Read more
Zinc finger protein 189 promotes the differentiation of lamina propria T helper 17.1 cells in dextran sulfate sodium-induced colitis Used in this study: B-Il17a-EGFP mice Read more
Pericytes protect rats and mice from sepsis-induced injuries by maintaining vascular reactivity and barrier function: implication of miRNAs and microvesicles Used in this study: B-Pdgfrb-iCre mice Read more
Cardiac disruption of SDHAF4-mediated mitochondrial complex II assembly promotes dilated cardiomyopathy Used in this study: Gene Editing Services Read more
Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia Used in this study: Immunodeficient B-NDG Mice Read more
Ex vivo engineered human plasma cells exhibit robust protein secretion and long-term engraftment in vivo Used in this study: B-NDG Mice;B-NDG hIL6 Mice Read more
Remodelling of tumour microenvironment by microwave ablation potentiates immunotherapy of AXL-specific CAR T cells against non-small cell lung cancer Used in this study: Immunodeficient B-NDG Mice Read more
Identification and characterization of innate lymphoid cells generated from pluripotent stem cells Used in this study: Immunodeficient B-NDG Mice Read more
Development of a bispecific antibody targeting PD-L1 and TIGIT with optimal cytotoxicity Used in this study: B-hTIGIT Mice Read more