B-hCTLA4 mice(C)

September 14, 2023

Biocytogen developed an CTLA4 humanized mice, the exon 2 of mouse Ctla4 gene that encodes the extracellular domain was replaced by human CTLA4 exon 2 in B-hCTLA4 mice(C). Then, confirmed that human CTLA4 protein was exclusively detectable in T cell subtypes of homozygous B-hCTLA4 mice(C). The mice can be used for preclinical pharmacodynamics studies of […]

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